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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5c1823fa71e29f41f7a64bf4de9bc0f577dea0efaff5b54af1bf59914c935c0' 
  AND token = 'UR8nN8Znk7yC3c/3U3zhuLYoMNP88tVU8iB12X8bAhg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}