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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39852167a31d865e03c87a603052c0baf1b322d97a5f14a1be26cfd204b45fc2' 
  AND token = 'pSR0hmfgV/I6kfsEA3tS5IQNLYMfpE3bmrrt7nmKnjw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}