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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7646186f2cd84509e12307605025a6c31d5b2501069647b9e48b7626330958d' 
  AND token = 'S2s3gOtfFBmoMrV8ENGC3lkDWO9r37XCasc3uH6y/I4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}