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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4060ac1f2d0e2f4cb3c17948cc8b877f64c7b09e43a61e7a6deb29eefc0379ae' 
  AND token = 'Z4Ta6s6FjncjTw/x7Q7V6EXOKjYujsFSXIJXWFcFTy0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}