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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75bc396a26b0a94cd7d463cfb00ad342fb1406d89ebd2864b505b11fdc0c83ce' 
  AND token = 'a27FIuEk0r8pwhMKqAzknMmRniy/uzBBvcCBjhvn2Y8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}