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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ca1da96e3d78213a90186a2b68c37e9f75d50224706c6384a24da5b7e097020' 
  AND token = 'd63SJ+zd9DDhfUoiDG7Aqgqrzo25EQHgEDX7kVhMtmY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}