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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4430d05143f6ec15d60e2a3b59f67a0a31499111ec5e5e6da28631db82fab2f2' 
  AND token = 'cIeVoto1ChilRLSUJ8sad6x3FNxMRCB/ePeyDzBa6GM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}