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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '606cd8241faf8f6e3bad343e52bd0538240fabbcd6e3b59dbe2d2389a0f1e123' 
  AND token = 'qkMV5KFB/+AspRnen9Rwx3pP/TOvdvV3NlJOohSaq+g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}