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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63b205d86ad8b8fa806613af351e229f501516018f186f96a6cb70ec7b91019a' 
  AND token = 'lx8O3hrHU3kBmMTj7nVz43RH7U6PFPajQF872fthQIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}