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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '338a2cf23d52736ebf6d57b4d33d46a9fc5e3641ea0d6a0383daf3a1c563f075' 
  AND token = 'ToZOiFxODjR24/JgNjvAY+AulvZOsZVAsYDZvZIZrxE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}