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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd263eb0b4f7d33d34ffeb6b819ad81d7d0457b817b2b0c8804e13b3700a4c8f5' 
  AND token = 'RTzjSN6yHtvG1kA0nzTT6e8nTParPxR7DW9DUsSxXYQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}