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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b4c7e61121b88be55cf7ed5992b32c6320b1b5c0a4807cb02b8dced435678cd' 
  AND token = 'BnVlFKtz4UUa/Hho8TMC5EyyTlZWu3AHw2b9vGqly2w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}