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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '634051e9b9267e891a2a258f3feefe7b7495436c1cc9eeee67f3d8529bbc2646' 
  AND token = 'kS9c/0DWbzlK5KoG75ArA0MLePjqPsXJqq9fctDve40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}