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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a17194b9733cc02b57bd6314ea50bbb5a2f42c4f7391677fb428041a11ba01b' 
  AND token = 'dWwe1wC7g1cPJvCuhe+cZUj33RlzQScvT0N0xoJTYSo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}