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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '650b7144366de1e8324fbbc0550016ab600c08362f9cdccb3243279bb744fcd4' 
  AND token = 'Ym7ZABDZ0Lh6RJ0K4/L9aW4i2QfG4dTCBQeqDNoVYGk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}