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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22cd9521201a90c4d7e5935897bdcb9f4cbaa35d9785d2e308791014f3e79dff' 
  AND token = 'SaDIZ6a2HbEQo8JNLv9p2ORvauajaXUBkdRW3qS6PGI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}