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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eecd18d4ce868b04670a6cb388eb001c6982bb716e26e5669382be8b9f5d6502' 
  AND token = 'R7YBb9LixijvgP7NCFEVnVIhNryoSbB+j56BPRtfaic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}