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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a49e16c4066034048ace0ce1d698f7b8ca43fe7b55872dd1a91589eb0a959fa' 
  AND token = 'JRVvlwteYcqF2UaWfAv59BYGa209NcCqK2v2iPo4bmY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}