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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3c9cec92a30b96b4ea1c67e9e5531589643d5548faa5f2de9b602eecb39fa04' 
  AND token = 'rFwa5aI5cLb44ru1ZJZPoNxrBPx6Xn3kSYoCRvBQm38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}