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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c0c0436eb18cf3af6950657526798fc99a6e794d865a74e1b558e33b92ce0fe' 
  AND token = 'tKANq2PDl5xftEHbK4R6pXdzFTDFF5/Ll5SAEbRYWr0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}