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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '403fcf451105b6abf787f8e5939f1533d987e9939ffa55c2e33499c7173872b2' 
  AND token = 'cV7t/UL4QCbPzZ43UsxMQaAaYwad2Eh5wabp4KKKeuw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}