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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21925abc5321d81f90430336b3962a2687c478687902ea1029fd04d0a26a395e' 
  AND token = 'ce7Jv7mkjG8Uwo/adKLcBNEJotMrBBEX0kcxmhYLJI0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}