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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '343a4f91bc27ef800019396c43ab630c99a2706775342f9ec651b1e318bac651' 
  AND token = 'c5CEGw0/RpxqUvvPZOu0NAiuwxmvk0GEVII/HM1zgAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}