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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ca338b1150b958db5723f6ccea87f30e3cf0be3132f88d1708633fd8e1b8c4c' 
  AND token = 'rRBD5aeMevi4ZnV0HEv3iNrH2FQyhRnQ+cSenyMjB1U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}