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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74f49b59104edbc2b77b9d848e0b73cd22a73b17ef9496400240f1f6b9871a5b' 
  AND token = 'I6U9JHYFQwp59X4LNYKpdmLEY2KDL7ETclo5oQMo8hg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}