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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af455573edc9e37ad606ac337618438259848725b18eefe9c53384a62e9a0c35' 
  AND token = 'kLaPXFkIPy4jq7ZlGVqsFnJdYFyXHy1ctJ1jsgHTk4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}