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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a14a4091970245f000e8d09c92210dd5c569bc4df073b7e0b1f0fee79c95677b' 
  AND token = 'mJcxXx/D/H2ohKim/wkfHgHB90TJFwPtIHmDTCOWkp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}