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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18aea0c5b169d7c0cde012750d77efc32cb2890d3b1f62145add45489730e0cc' 
  AND token = 'jNIFXwh5de0EVp5txQ4dizH4BTOT+NUAMX9A1C6AHTY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}