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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9dc3f720bfce16674a3f78c6ab86bec355d2036b44b2687d77874c3452287199' 
  AND token = 'EX+uksZUtd+LmR83mXwEOGsH+PDpCWG6hHPrb6Wc1Vk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}