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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d5dbd473f4c0535f40e34ebf41ed403a62e3b536be200a68954c1d972ba9141' 
  AND token = 'k6H7j+BCtgPs4WM9mtx45oHTlKHAmoMkM+ywT/en92c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}