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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e5a942cf35d03b1acc18b17b897ae9e9ced0c78f7446de66af82d51071584f4' 
  AND token = 'qRsG/K1JnEss4XS2xzEXwr2zZeTwQCuWwn4542b6TdQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}