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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee8dff569ae5dab31c4a83f3d4acd1651c15654261b40695a05f9086166f66f0' 
  AND token = 'deeRMR2LoRCSBAoBxZHAxTxPK33C58oQvZo2/KwFJKA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}