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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '152d439238132af03899ef9c20a26687d87d65be32707d9e529561eecf483542' 
  AND token = 'IPT2sto5j/3g6K9xz0wpYjpzHkEUhep6vkPt6tfjCAc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}