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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6d3b61854dd17dafd1f85dc07a97564f3b745c94ce4c01dd488978a2fdb06e7' 
  AND token = '3mO7ZcgyM7rpGuqSpuS6EAWve7hCVoUsG9WcW6h3ivc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}