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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6b43a5a3007451eb785fe1c63724c3de06274e488f45e00725ba181d8e66e9e' 
  AND token = '4ymNAFJ2CCNQI5M9vu59MAr39sdi5WamWFuAvGqqd80=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}