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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65ba60721fdabdfb202b673b3ccf1da537b5092fb63fde31bdda119dd4353b20' 
  AND token = 'OIcT4PTagUOtJ5aKAWeMzn+WEyMUKcKJBE9Y/4L1+Wc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}