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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65f9e64f30ab0b2c8c830b4a34de8211ee9ad7e0c14786716e9fad38b92de309' 
  AND token = '5bHWCZEZ9s2P4OQYE+hP824STGa679h3DxDkmcKNpEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}