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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1204e637e37c569997749212a12c178146d227a3598d23a976baace8b32bad5c' 
  AND token = 'aTDerO2IEoCjoMyhxp0dWg/p+9RAeYvRSV+MYiWuj+o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}