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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2d6c30555a1846ef34d5a50e049e4cc74cf441d60c55ced82e46449f9ff0873' 
  AND token = 'IjKjQChSe/jMXY9L4yaWIPG1LsN7R/R0FlEUHYT7NMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}