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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '76cfe74fdef91baf075e34b51404e2b91bc88931c21cb83af70a8edaf3cbc8c1' 
  AND token = 'v9NRiXPjaS5fMWnE5z/stWwvyNNEhUjhlIaMr9U7604=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}