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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8045e6249b28d552d5fabe5953318b4bd8831a926ec078c6607f53d2450861fa' 
  AND token = 'ro2cNfNKvbmYL0FNFEvNnXMecy/dV8IEsQRKy+LmcGA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}