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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f4ebe05514d08acd6abcf281a8d56777064af21878d117a0c7623eab17c0fca' 
  AND token = 'E4bTUHJMNSkhhbyEph4jbm4XVolndR9CY9YgJ5G763c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}