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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0ddf854845fa47971d90fca4180f18309f903e94a85c36ec39da6a22145c004' 
  AND token = 'iN59XOpoUnI0yUyEIGla9/0iX7Vng7m0C6Rar0CVRjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}