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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a69bfebc22156a24ba0796ce2f007cf3fa5edfe4cd85569c38d098109149467f' 
  AND token = 'GXAVaL4VsLX4vBhvjX99O9VHeWPW6hrvaw1wQKs7JOA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}