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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4043e8d33d432501ca858f01953579d60ea162bd1be80fed0633eb83db957f8f' 
  AND token = 'xdNAGALL/BX8Lqknenok+fN5t5rmlxvTneN1iL4bqzs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}