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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a989f9899938ce43d65a49d872fe7d1fc388a042ed6e5ce5d29e6382905a61e6' 
  AND token = 'YgViA3LgDa0CDbPE9Li/LFzNf6WprywuWCnij2q8ZK8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}