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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '972ef908c102b086204e1b54f13d2317b7b370b61f3eb9f1eba4c4c0ebac4135' 
  AND token = '3ud0rQAGxq09u2DHCdc4EWOx7pXhWfZjLhzDus+Q82Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}