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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d1baceeaa8d4a8c281d10d5afd8dabcace8471cc38eb151d1a7651cec604a26' 
  AND token = 'kPWpTUDQBY9/Bw7XTFZEIu61ia78IlVAIkAgurF/W7g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}