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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c449a5e0b0444ee9dcd24671e863a3ae3838afdff3fa66a4395c5d4d8c0e966' 
  AND token = 'Vq+lmG9VDpQh9u5eAwNQUl9K3F8CLJYqpPy3W3fZ6X0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}