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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7117e580f42e0cf06e9076127e6d6f2778da5371f5f6440d60430657b2df758b' 
  AND token = 'NN+9XZz9DEBJ77D5dmbM0xllRkuRo+kxMFc4Jycnm/c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}